Vitamin D Research Today is a free monthly online journal that collates and summarizes the latest research about Vitamin D, including details on sources, melanin, benefits, deficiency, supplements, calcium absorption.

Vitamin D regulation of cathelicidin in the skin: toward a renaissance of vitamin D in dermatology?

Segaert S

Department of Dermatology, University Hospital Leuven, Belgium. Siegfried.Segaert@med.kuleuven.be

1,25-Dihydroxyvitamin D(3), the active form of vitamin D, is a major regulator of the expression of the cationic antimicrobial peptide cathelicidin, not only in monocytes but also in epidermal keratinocytes. The involvement of cathelicidin in wound healing and skin diseases as diverse as psoriasis, rosacea, and atopic dermatitis may create new opportunities for the use of vitamin D in dermatology.

Published 13 March 2008 in J Invest Dermatol, 128(4): 773-5.
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