Vitamin D Research Today is a free monthly online journal that collates and summarizes the latest research about Vitamin D, including details on sources, melanin, benefits, deficiency, supplements, calcium absorption.

Dietary intake of calcium, vitamin D, phosphorus and the risk of prostate cancer.

Tavani A, Bertuccio P, Bosetti C, Talamini R, Negri E, Franceschi S, Montella M, La Vecchia C

Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milano, Italy. tavani@marionegri.it

OBJECTIVES: A relation of prostate cancer risk with calcium, vitamin D and phosphorus has been suggested, but remains controversial. METHODS: A case-control study was conducted in Italy in 1991-2002. Cases were 1294 men with incident prostate cancer, and controls were 1451 men admitted to hospital for acute non-neoplastic diseases. Odds ratios (OR) and the corresponding 95% confidence intervals (CI) were estimated using unconditional multiple logistic regression. RESULTS: Compared to the lowest one quintile of dietary calcium intake the OR was 1.18 for the highest, 1.01 for an increment of 622 mg/day of calcium, and 1.29 (95% CI 0.78-2.13) for 2000 mg/day or more of calcium. The OR of prostate cancer for the highest quintile of dietary intake of vitamin D and phosphorus were 1.33 and 1.20 respectively. CONCLUSIONS: This study shows no material association of dietary intake of calcium, vitamin D and phosphorus with prostate cancer risk.

Published 21 June 2005 in Eur Urol, 48(1): 27-33.
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