Vitamin D Research Today is a free monthly online journal that collates and summarizes the latest research about Vitamin D, including details on sources, melanin, benefits, deficiency, supplements, calcium absorption.

Update on the etiology of tooth resorption in domestic cats.

Reiter AM, Lewis JR, Okuda A

Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104-6010, USA. reiter@vet.upenn.edu

Based on recent findings of increased vitamin D activity in cats with feline odontoclastic resorptive lesions (FORL), the present article provides further clues on the possible etiology of FORL. Microscopic features of FORL and other peculiarities of feline permanent teeth are compared with pathologic findings obtained from experimental studies in other species. Administration of excess vitamin D or vitamin D metabolites in laboratory animals caused changes to dental and periodontal tissues that resemble histopathologic features of teeth from cats with FORL. Chronic excess dietary vitamin D may be the long-sought cause of multiple tooth resorption in domestic cats. It may also provide a basis for future research on idiopathic hypercalcemia and renal disease in the same species.

Published 27 June 2005 in Vet Clin North Am Small Anim Pract, 35(4): 913-42, vii.
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